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Morpholino and Zebrafish: Benefits and Applications

One important strategy used during drug discovery and development is the modification of the expression of a particular gene in an animal model. This.

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Alternative Models for Rare Disease Research

Definition of rare disease When is a disease considered rare? The definition of a rare disease depends largely on its incidence and so the FDA.

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Transgenic Animal Models in Biomedical Research

Thanks to the Human Genome Project completed in 2003, now we have a detailed catalog of human genome variation associated with many diseases. Despite.

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Ex Vivo vs In Vitro: Understand the Difference

Numerous experimental models currently used in the preclinical arena can aid the research and development of new pharmaceutical compounds and Drug.

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Alternatives to Animal Models

The final aim for every medicine is to be as much efficacious as possible while minimizing the potential adverse effects that could arise from the.

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Zebrafish Screening: Studies That Can be Conducted with Zebrafish

The Zebrafish (Danio rerio) is becoming a highly popular animal model in research. There are several reasons for this choice including not only its.

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Drug Development Timeline: How New Drugs Are Discovered

When we walk into a pharmacy, we see many drugs which can be prescribed by a doctor, but every single drug on the shelf has passed very stringent.

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Developmental Toxicity: Testing Using Alternative Models

Developmental toxicity plays an important role in Drug Discovery as it studies the toxic effects a chemical or substance can have on an embryo or.

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The FET Test: Uses and Models

The FET (fish embryo toxicity) Test has been designed as an alternative to the acute toxicity test. The acute toxicity test exposes live fish to.

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Reproductive Toxicology: Using Alternative Models for Testing

Drug Discovery and pharmaceutical research is designed around gathering data for a full understanding of the toxicity, safety, and efficacy of the.

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