Testing Reproductive Toxicity in Early Drug Discovery
Reproductive toxicity tests are essential to test and study the reproductive cycle in humans. The testing examines the reproductive cycle, from.
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What is Good Laboratory Practice (GLP)?
The history of science shows a clear tendency of ever-growing expectations and higher standards. The scientific community takes pride in the solid.
Fluorescence Polarization Assay with Zebrafish
Early drug discovery uses a wide variety of tests and assays in order to determine whether a new hit can continue to be developed and enter.
What is a New Molecular Entity and How does it affect Drug Discovery
The FDA (the US Food and Drug Administration) defines a new molecular entity (NME) as a new drug whose active ingredient is a chemical substance that.
In Silico for Drug Discovery
The in silico method represents an increasing role in drug discovery as technology becomes more sophisticated. It is fast becoming a cost-effective.
What is CRISPR Cas13 and How is it Used?
The development of new medicines that aim to treat complex diseases is driven by new tools continuously arising in modern science. Both the social.
Morpholino and Zebrafish: Benefits and Applications
One important strategy used during drug discovery and development is the modification of the expression of a particular gene in an animal model. This.
Alternative Models for Rare Disease Research
Definition of rare disease When is a disease considered rare? The definition of a rare disease depends largely on its incidence and so the FDA.
Transgenic Animal Models in Biomedical Research
Thanks to the Human Genome Project completed in 2003, now we have a detailed catalog of human genome variation associated with many diseases. Despite.
Ex Vivo vs In Vitro: Understand the Difference
Numerous experimental models currently used in the preclinical arena can aid the research and development of new pharmaceutical compounds and Drug.