The process of Drug Discovery is a complex issue that involves large amounts of testing and multiple validation tests to achieve drug efficacy, and.
The Drug Discovery process has a problem. Research, development, and FDA approval for new drugs can take on average up to 10 to 15 years, and it.
There are two efficient screening methods which are widely used to sort out compounds in early Drug Discovery. These methods include High Throughput.
Animal models have been used for centuries as an alternative to humans in scientific research. Small mammals, such as mice and rats, have typically.
In recent decades Zebrafish (Danio rerio) have proven to be a valid subject for vertebrate genetic disease studies. Their use is both innovative and.
Transgenic animal models are an important tool for the discovery of human disease-related mutations as well as the drugs that treat them. Genetic.
The 3Rs of Animal Research (Replacement, Reduction and Refinement) were created more than 50 years ago as a framework for performing more humane and.
During novel Drug Discovery and Development processes researchers typically begin with in vitro testing and then move to in vivo models. But what.