What is High Throughput Screening in Drug Discovery?
The process of Drug Discovery is a complex issue that involves large amounts of testing and multiple validation tests to achieve drug efficacy, and.
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Toxicity Screening: 7 Strategies for Preclinical Research
The Drug Discovery process has a problem. Research, development, and FDA approval for new drugs can take on average up to 10 to 15 years, and it.
What is an In Vivo Test?
Drug Discovery and Development is a long process that goes through several phases, often taking over a decade. The process includes different in.
High Content Screening: What is it, Methodologies and Best Practices
There are two efficient screening methods which are widely used to sort out compounds in early Drug Discovery. These methods include High Throughput.
Zebrafish Research: Everything You Need to Know
As an animal model, zebrafish (Danio rerio) have swum to prominence in the last two decades. A combination of genetic, physical, and economic factors.
How can Zebrafish Embryos Be Used As an Animal Model
Animal models have been used for centuries as an alternative to humans in scientific research. Small mammals, such as mice and rats, have typically.
Zebrafish Genome Compared to Human: How Are They Similar
In recent decades Zebrafish (Danio rerio) have proven to be a valid subject for vertebrate genetic disease studies. Their use is both innovative and.
Fluorescent Transgenic Zebrafish: How Are They Used in Drug Screening?
Transgenic animal models are an important tool for the discovery of human disease-related mutations as well as the drugs that treat them. Genetic.
The 3Rs of Animal Research: Ethics and Alternative Models
The 3Rs of Animal Research (Replacement, Reduction and Refinement) were created more than 50 years ago as a framework for performing more humane and.
In Vivo vs In Vitro: Differences in Early Drug Discovery
During novel Drug Discovery and Development processes researchers typically begin with in vitro testing and then move to in vivo models. But what.