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European and US agencies Leading to Promote New Alternative Methods in Research

The Food and Drug Administration (FDA) is pushing for alternative models in drug development is a positive step forward for both patients and the.

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Adverse Outcome Pathways for Molecular Screening

Understanding the potential risk to humans of many chemicals and toxins that surround us in our daily lives is essential for health preservation..

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Which are the Main American Regulatory Agencies?

Regulatory agencies in the human toxicology field are responsible for protecting and promoting public health through the control of the toxicity and.

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Which is the European Centre for the Validation of Alternative Methods (ECVAM) role in promoting the 3Rs?

The ECVAM (European Centre for the Validation of Alternative Methods) plays an important role in ensuring that alternative testing methods are.

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Are zebrafish a good model for studying regeneration, such as heart or neuron regeneration?

Cardiovascular diseases and neurodegenerative diseases are predominant causes of death, morbidity, and disability in the world, with an increasing.

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What are the OECD and ICH Guidelines? What do they have in common?

The OECD (Organisation for Economic Co-operation and Development) and the ICH (International Council for Harmonisation of Technical Requirements for.

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Sperm Cryopreservation in Zebrafish: Methods and Advantages

Sperm cryopreservation is the method of freezing zebrafish sperm, similar to the way human sperm can be frozen for later use. This method allows a.

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Teratogenicity Testing: Screening Drugs for Birth Defects

Teratogens are substances that can cause physical or functional defects in human embryos or fetuses. Since the Thalidomide medical disaster in the.

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What do Antisense Oligonucleotides do?

What are Antisense oligonucleotides? Antisense Oligonucleotides (ASO) are short nucleotide chains of 8-50 nucleotides that present the structural.

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What is mCherry and How is it used?

mCherry is a fluorescent protein that presents a monomeric structure of 236 amino acids and a mass of 26.7 kDa. Fluorescent proteins are members of a.

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