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Schizophrenia Assessment in Zebrafish

Schizophrenia is a chronic psychiatric disorder characterized by continuous or relapsing episodes of psychosis that can alter severely normal brain.

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How zebrafish can be used to assess toxicity in reproduction and development

Reproductive toxicology studies how drugs affect the reproductive system, including harmful side effects that can impact the parents (reproduction).

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Zebrafish as a Model Organism in Research: Methods and Benefits

In vivo model organisms are popular tools for biomedicine researchers globally. They share many genes with humans, have short generation periods and.

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The 3Rs of Animal Research: Applications & Alternative Models

The 3Rs Principles provide a foundation for ethical and more humane animal research. They have been implemented in international legislations and.

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From Preclinical Studies to Clinical Trials: Steps and Process

The Drug Discovery and Developmentprocess is divided into several phases, from the initial efficacy and safety assays performed in vitro and in.

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How zebrafish helps in preclinical eye disease research

Eye diseases are a heterogeneous group of diseases affecting the eye with different causes and severity. The most common eye diseases are related to.

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How assays are set up and validated based on guidelines

Laboratory assays set up for Pre-Clinical and Clinical Trials must fulfill strict criteria in every aspect of the assessment including the Protocol,.

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Neurotoxicity Assay Using Alternative Models

A wide variety of substances like chemicals, pollutants, or drugs can damage the nervous system, causing neurotoxicity and leading to neurological.

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Dose Range Finding Studies in Preclinical Research

Before any drug can be given to a human subject its safety and efficacy must be assessed. The Dose Range Finding (DRF) assay is an important test in.

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Alternative Animal Models for Neurogenerative Diseases

Neurodegenerative diseases (NDs) are disorders caused by de progressive and irreversible destruction of the nervous tissue that produces memory and.

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