Morpholino and Zebrafish: Benefits and Applications
One important strategy used during drug discovery and development is the modification of the expression of a particular gene in an animal model. This.
Alternative Models for Rare Disease Research
Definition of rare disease When is a disease considered rare? The definition of a rare disease depends largely on its incidence and so the FDA.
Transgenic Animal Models in Biomedical Research
Thanks to the Human Genome Project completed in 2003, now we have a detailed catalog of human genome variation associated with many diseases. Despite.
Alternatives to Animal Models
The final aim for every medicine is to be as much efficacious as possible while minimizing the potential adverse effects that could arise from the.
Zebrafish Screening: Studies That Can be Conducted with Zebrafish
The Zebrafish (Danio rerio) is becoming a highly popular animal model in research. There are several reasons for this choice including not only its.
Drug Development Timeline: How New Drugs Are Discovered
When we walk into a pharmacy, we see many drugs which can be prescribed by a doctor, but every single drug on the shelf has passed very stringent.
Developmental Toxicity: Testing Using Alternative Models
Developmental toxicity plays an important role in Drug Discovery as it studies the toxic effects a chemical or substance can have on an embryo or.
The FET Test: Uses and Models
The FET (fish embryo toxicity) Test has been designed as an alternative to the acute toxicity test. The acute toxicity test exposes live fish to.
Reproductive Toxicology: Using Alternative Models for Testing
Drug Discovery and pharmaceutical research is designed around gathering data for a full understanding of the toxicity, safety, and efficacy of the.
Define CRISPR: What Is It and How Is It Used in Drug Discovery
The latest tools in the Drug Discovery toolbox can sometimes be difficult to decipher, especially with new forms of genetic engineering popping up.