OECD guidelines for Chronic Toxicity studies
Chronic Toxicity studies are a form of assays that are likely to affect the health of a subject if exposed to a substance repeatedly or constantly.
drug discovery
Lead Optimization Strategies to Further Drug Discovery
Before a drug obtains market approval, it must go through a series of pre-clinical and clinical studies which ensure that the compound is safe and.
How zebrafish can be used to assess toxicity in reproduction and development
Reproductive toxicology studies how drugs affect the reproductive system, including harmful side effects that can impact the parents (reproduction).
From Preclinical Studies to Clinical Trials: Steps and Process
The Drug Discovery and Developmentprocess is divided into several phases, from the initial efficacy and safety assays performed in vitro and in.
How zebrafish helps in preclinical eye disease research
Eye diseases are a heterogeneous group of diseases affecting the eye with different causes and severity. The most common eye diseases are related to.
How assays are set up and validated based on guidelines
Laboratory assays set up for Pre-Clinical and Clinical Trials must fulfill strict criteria in every aspect of the assessment including the Protocol,.
Neurotoxicity Assay Using Alternative Models
A wide variety of substances like chemicals, pollutants, or drugs can damage the nervous system, causing neurotoxicity and leading to neurological.
Dose Range Finding Studies in Preclinical Research
Before any drug can be given to a human subject its safety and efficacy must be assessed. The Dose Range Finding (DRF) assay is an important test in.
Alternative Animal Models for Neurogenerative Diseases
Neurodegenerative diseases (NDs) are disorders caused by de progressive and irreversible destruction of the nervous tissue that produces memory and.
Endocrine Disrupting Studies in Zebrafish
Exposure to harmful chemicals surrounds us in our daily lives. From the water-plastic bottles consume to the non-stick pans we use to cook, the toys.