--- title: Blog | Sample HubSpot User (6) description: (6) --- [![Bio Bide](https://blog.biobide.com/hs-fs/hubfs/raw_assets/public/Biobide_August2020/images/logo_small_hq_5.png?width=413&height=135&name=logo_small_hq_5.png "Bio Bide")](https://www.biobide.es/) ![Zebra Fish Partner](https://blog.biobide.com/hs-fs/hubfs/raw_assets/public/Biobide_August2020/images/partner.png?width=133&height=95&name=partner.png) [![Bio Bide](https://blog.biobide.com/hs-fs/hubfs/raw_assets/public/Biobide_August2020/images/logo_small_hq_5.png?width=413&height=135&name=logo_small_hq_5.png "Bio Bide")](https://www.biobide.es/) - [Home](https://www.biobide.es/) - COMPANY - [About Us](https://www.biobide.es/about-us) - [Our Technology](https://www.biobide.es/our-technology) - Services - [Standard Assays](https://www.biobide.es/standard-assays) - [Tailor Made Solutions](https://www.biobide.es/tailor-made-solutions) - [News](https://www.biobide.es/news) - Publications - [Posters](https://www.biobide.es/posters) - [Articles](https://www.biobide.es/articles) - [Testimonials](https://biobide.com/testimonials) - [Job Positions](https://biobide.com/job-positions) - [Blog](https://blog.biobide.com/) - [Contact](https://www.biobide.es/contact) ## Search form Search [![Schizophrenia Assessment in Zebrafish](https://blog.biobide.com/hs-fs/hubfs/Copia-de-FEATURED-IMAGE-BLOG_1-1.webp?width=960&height=500&name=Copia-de-FEATURED-IMAGE-BLOG_1-1.webp "Schizophrenia Assessment in Zebrafish")](https://blog.biobide.com/schizophrenia-assessment-in-zebrafish) ## [Schizophrenia Assessment in Zebrafish](https://blog.biobide.com/schizophrenia-assessment-in-zebrafish) Schizophrenia is a chronic psychiatric disorder characterized by continuous or relapsing episodes of psychosis that can alter severely normal brain. [read more](https://blog.biobide.com/schizophrenia-assessment-in-zebrafish) [![How zebrafish can be used to assess toxicity in reproduction and development](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(6).png?width=960&height=500&name=Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(6).png "How zebrafish can be used to assess toxicity in reproduction and development")](https://blog.biobide.com/how-zebrafish-can-be-used-to-assess-toxicity-in-reproduction-and-development-1) ## [How zebrafish can be used to assess toxicity in reproduction and development](https://blog.biobide.com/how-zebrafish-can-be-used-to-assess-toxicity-in-reproduction-and-development-1) Reproductive toxicology studies how drugs affect the reproductive system, including harmful side effects that can impact the parents (reproduction). [read more](https://blog.biobide.com/how-zebrafish-can-be-used-to-assess-toxicity-in-reproduction-and-development-1) [![Zebrafish as a Model Organism in Research: Methods and Benefits](https://blog.biobide.com/hs-fs/hubfs/Zebrafish-as-a-model-organism-in-research.jpg?width=960&height=500&name=Zebrafish-as-a-model-organism-in-research.jpg "Zebrafish as a Model Organism in Research: Methods and Benefits")](https://blog.biobide.com/zebrafish-as-a-model-organism-in-research-methods-and-benefits) ## [Zebrafish as a Model Organism in Research: Methods and Benefits](https://blog.biobide.com/zebrafish-as-a-model-organism-in-research-methods-and-benefits) In vivo model organisms are popular tools for biomedicine researchers globally. They share many genes with humans, have short generation periods and. [read more](https://blog.biobide.com/zebrafish-as-a-model-organism-in-research-methods-and-benefits) [![The 3Rs of Animal Research: Applications & Alternative Models](https://blog.biobide.com/hs-fs/hubfs/FEATURED%20IMAGE%20BLOG%20(3).jpg?width=960&height=500&name=FEATURED%20IMAGE%20BLOG%20(3).jpg "The 3Rs of Animal Research: Applications & Alternative Models")](https://blog.biobide.com/the-3rs) ## [The 3Rs of Animal Research: Applications & Alternative Models](https://blog.biobide.com/the-3rs) The 3Rs Principles provide a foundation for ethical and more humane animal research. They have been implemented in international legislations and. [read more](https://blog.biobide.com/the-3rs) [![From Preclinical Studies to Clinical Trials: Steps and Process](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(5).png?width=960&height=500&name=Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(5).png "From Preclinical Studies to Clinical Trials: Steps and Process")](https://blog.biobide.com/from-preclinical-studies-to-clinical-trials-steps-and-process) ## [From Preclinical Studies to Clinical Trials: Steps and Process](https://blog.biobide.com/from-preclinical-studies-to-clinical-trials-steps-and-process) The Drug Discovery and Developmentprocess is divided into several phases, from the initial efficacy and safety assays performed in vitro and in. [read more](https://blog.biobide.com/from-preclinical-studies-to-clinical-trials-steps-and-process) [![How zebrafish helps in preclinical eye disease research](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(4)-1.png?width=960&height=500&name=Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(4)-1.png "How zebrafish helps in preclinical eye disease research")](https://blog.biobide.com/how-zebrafish-helps-in-preclinical-eye-disease-research) ## [How zebrafish helps in preclinical eye disease research](https://blog.biobide.com/how-zebrafish-helps-in-preclinical-eye-disease-research) Eye diseases are a heterogeneous group of diseases affecting the eye with different causes and severity. The most common eye diseases are related to. [read more](https://blog.biobide.com/how-zebrafish-helps-in-preclinical-eye-disease-research) [![How assays are set up and validated based on guidelines](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20FEATURED%20IMAGE%20BLOG-Apr-14-2023-11-33-39-5828-AM.jpg?width=960&height=500&name=Copia%20de%20FEATURED%20IMAGE%20BLOG-Apr-14-2023-11-33-39-5828-AM.jpg "How assays are set up and validated based on guidelines")](https://blog.biobide.com/how-assays-are-set-up-and-validated-based-on-guidelines) ## [How assays are set up and validated based on guidelines](https://blog.biobide.com/how-assays-are-set-up-and-validated-based-on-guidelines) Laboratory assays set up for Pre-Clinical and Clinical Trials must fulfill strict criteria in every aspect of the assessment including the Protocol,. [read more](https://blog.biobide.com/how-assays-are-set-up-and-validated-based-on-guidelines) [![Neurotoxicity Assay Using Alternative Models](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(3)-1.png?width=960&height=500&name=Copia%20de%20Copia%20de%20FEATURED%20IMAGE%20BLOG%20(3)-1.png "Neurotoxicity Assay Using Alternative Models")](https://blog.biobide.com/neurotoxicity-assay-using-alternative-models) ## [Neurotoxicity Assay Using Alternative Models](https://blog.biobide.com/neurotoxicity-assay-using-alternative-models) A wide variety of substances like chemicals, pollutants, or drugs can damage the nervous system, causing neurotoxicity and leading to neurological. [read more](https://blog.biobide.com/neurotoxicity-assay-using-alternative-models) [![Dose Range Finding Studies in Preclinical Research](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20FEATURED%20IMAGE%20BLOG-Apr-12-2023-01-30-21-4683-PM.png?width=960&height=500&name=Copia%20de%20FEATURED%20IMAGE%20BLOG-Apr-12-2023-01-30-21-4683-PM.png "Dose Range Finding Studies in Preclinical Research")](https://blog.biobide.com/dose-range-finding-studies-in-preclinical-research) ## [Dose Range Finding Studies in Preclinical Research](https://blog.biobide.com/dose-range-finding-studies-in-preclinical-research) Before any drug can be given to a human subject its safety and efficacy must be assessed. The Dose Range Finding (DRF) assay is an important test in. [read more](https://blog.biobide.com/dose-range-finding-studies-in-preclinical-research) [![Alternative Animal Models for Neurogenerative Diseases](https://blog.biobide.com/hs-fs/hubfs/Copia%20de%20FEATURED%20IMAGE%20BLOG-May-16-2023-01-04-17-4247-PM.jpg?width=960&height=500&name=Copia%20de%20FEATURED%20IMAGE%20BLOG-May-16-2023-01-04-17-4247-PM.jpg "Alternative Animal Models for Neurogenerative Diseases")](https://blog.biobide.com/alternative-animal-models-for-neurogenerative-diseases) ## [Alternative Animal Models for Neurogenerative Diseases](https://blog.biobide.com/alternative-animal-models-for-neurogenerative-diseases) Neurodegenerative diseases (NDs) are disorders caused by de progressive and irreversible destruction of the nervous tissue that produces memory and. 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