High Content Screening: What is it, Methodologies and Best Practices
There are two efficient screening methods which are widely used to sort out compounds in early Drug Discovery. These methods include High Throughput.
zebrafish
How Are Zebrafish Used in Research?
As an animal model, zebrafish (Danio rerio) have swum to prominence in the last two decades. A combination of genetic, physical, and economic factors.
How can Zebrafish Embryos Be Used As an Animal Model
Animal models have been used for centuries as an alternative to humans in scientific research. Small mammals, such as mice and rats, have typically.
Zebrafish Genome Compared to Human: How Are They Similar
In recent decades Zebrafish (Danio rerio) have proven to be a valid subject for vertebrate genetic disease studies. Their use is both innovative and.
Fluorescent Transgenic Zebrafish: How Are They Used in Drug Screening?
Transgenic animal models are an important tool for the discovery of human disease-related mutations as well as the drugs that treat them. Genetic.
The 3Rs of Animal Research: Ethics and Alternative Models
The 3Rs of Animal Research (Replacement, Reduction and Refinement) were created more than 50 years ago as a framework for performing more humane and.
In Vivo vs In Vitro: Differences in Early Drug Discovery
During novel Drug Discovery and Development processes researchers typically begin with in vitro testing and then move to in vivo options. But what.
Zebrafish as a Model Organism in Research: Methods and Benefits
In vivo model organisms are popular tools for biomedicine researchers globally. They share many genes with humans, have short generation periods and.